CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.840 | Son of Sevenless (SoS) protein; Chain S, domain 2 |
|
1.10.840.10 | Ras guanine-nucleotide exchange factors catalytic domain |
Domain Context
CATH Clusters
| Superfamily | Ras guanine-nucleotide exchange factors catalytic domain |
| Functional Family | son of sevenless homolog 1 isoform X2 |
Enzyme Information
UniProtKB Entries (1)
| Q07889 |
SOS1_HUMAN
Homo sapiens
Son of sevenless homolog 1
|
PDB Structure
| PDB | 2II0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proc.Natl.Acad.Sci.Usa
|