CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Exoribonuclease 2

Enzyme Information

3.1.13.1
Exoribonuclease II.
based on mapping to UniProt P30850
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for single-stranded RNA. -!- The enzyme processes 3'-terminal extra-nucleotides of monomeric tRNA precursors, following the action of EC 3.1.26.5. -!- Similar enzymes: RNase Q, RNase BN, RNase PIII, RNase Y. -!- Formerly EC 3.1.4.20.

UniProtKB Entries (1)

P30850
RNB_ECOLI
Escherichia coli K-12
Exoribonuclease 2

PDB Structure

PDB 2ID0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Basis for Processivity and Single-Strand Specificity of RNase II.
Zuo, Y., Vincent, H.A., Zhang, J., Wang, Y., Deutscher, M.P., Malhotra, A.
Mol.Cell