1 keywords

CATH Domain 2i4zB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

P37231
PPARG_HUMAN
Homo sapiens
Peroxisome proliferator-activated receptor gamma

PDB Structure

PDB 2I4Z
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands
Pochetti, G., Godio, C., Mitro, N., Caruso, D., Galmozzi, A., Scurati, S., Loiodice, F., Fracchiolla, G., Tortorella, P., Laghezza, A., Lavecchia, A., Novellino, E., Mazza, F., Crestani, M.
J.Biol.Chem.