CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family aspartoacylase

Enzyme Information

3.5.1.15
Aspartoacylase.
based on mapping to UniProt P45381
N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate.

UniProtKB Entries (1)

P45381
ACY2_HUMAN
Homo sapiens
Aspartoacylase

PDB Structure

PDB 2I3C
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Bitto, E., Bingman, C.A., Wesenberg, G.E., McCoy, J.G., Phillips, G.N.
Proc.Natl.Acad.Sci.Usa