CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt Q57DY1
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

Q57DY1
RISB1_BRUAB
Brucella abortus bv. 1 str. 9-941
6,7-dimethyl-8-ribityllumazine synthase 1

PDB Structure

PDB 2I0F
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
Klinke, S., Zylberman, V., Bonomi, H.R., Haase, I., Guimaraes, B.G., Braden, B.C., Bacher, A., Fischer, M., Goldbaum, F.A.
J.Mol.Biol.