CATH Classification

Domain Context

CATH Clusters

Superfamily P1 Nuclease
Functional Family Phospholipase C

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt P09598
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P09598
PHLC_BACCE
Bacillus cereus
Phospholipase C

PDB Structure

PDB 2HUC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural studies examining the substrate specificity profiles of PC-PLC(Bc) protein variants.
Benfield, A.P., Goodey, N.M., Phillips, L.T., Martin, S.F.
Arch.Biochem.Biophys.