CATH Classification

Domain Context

CATH Clusters

Superfamily Bacterial DNA polymerase III alpha subunit, thumb domain
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9XDH5
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9XDH5
DPO3A_THEAQ
Thermus aquaticus
DNA polymerase III subunit alpha

PDB Structure

PDB 2HPI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Bailey, S., Wing, R.A., Steitz, T.A.
Cell(Cambridge,Mass.)