CATH Classification

Domain Context

CATH Clusters

Superfamily Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
Functional Family Naphthalene 1,2-dioxygenase system, large oxygenase component

Enzyme Information

1.14.12.12
Naphthalene 1,2-dioxygenase.
based on mapping to UniProt P0A111
Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).
-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A111
NDOB_PSEU8
Pseudomonas sp. C18
Naphthalene 1,2-dioxygenase system, large oxygenase component

PDB Structure

PDB 2HML
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase.
Ferraro, D.J., Okerlund, A.L., Mowers, J.C., Ramaswamy, S.
J.Bacteriol.