CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphofructokinase domain
Functional Family

Enzyme Information

2.7.1.11
6-phosphofructokinase.
based on mapping to UniProt O15648
ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.
-!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors. -!- UTP, CTP and ITP can act as donors. -!- Not identical with EC 2.7.1.105.

UniProtKB Entries (1)

O15648
PFKA_TRYBB
Trypanosoma brucei brucei
ATP-dependent 6-phosphofructokinase

PDB Structure

PDB 2HIG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei.
Martinez-Oyanedel, J., McNae, I.W., Nowicki, M.W., Keillor, J.W., Michels, P.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.
J.Mol.Biol.