CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.470.10
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt O15382
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

O15382
BCAT2_HUMAN
Homo sapiens
Branched-chain-amino-acid aminotransferase, mitochondrial

PDB Structure

PDB 2HGW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS.
Yennawar, N.H., Islam, M.M., Conway, M., Wallin, R., Hutson, S.M.
J.Biol.Chem.