CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Rho-associated protein kinase 2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q28021
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q28021
ROCK2_BOVIN
Bos taurus
Rho-associated protein kinase 2

PDB Structure

PDB 2H9V
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632
Yamaguchi, H., Miwa, Y., Kasa, M., Kitano, K., Amano, M., Kaibuchi, K., Hakoshima, T.
J.Biochem.(Tokyo)