CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P9WI77
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P9WI77
PKNE_MYCTU
Mycobacterium tuberculosis H37Rv
Serine/threonine-protein kinase PknE

PDB Structure

PDB 2H34
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A Conserved Dimer and Global Conformational Changes in the Structure of apo-PknE Ser/Thr Protein Kinase from Mycobacterium tuberculosis.
Gay, L.M., Ng, H.L., Alber, T.
J.Mol.Biol.