CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1400
Functional Family Ferrochelatase

Enzyme Information

4.99.1.1
Protoporphyrin ferrochelatase.
based on mapping to UniProt P32396
Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
-!- The enzyme catalyzes the terminal step in the heme biosynthesis pathways of eukaryotes and Gram-negative bacteria.

UniProtKB Entries (1)

P32396
HEMH_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ferrochelatase

PDB Structure

PDB 2H1W
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX
Hansson, M.D., Karlberg, T., Rahardja, M.A., Al-Karadaghi, S., Hansson, M.
Biochemistry