CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P21836
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P21836
ACES_MOUSE
Mus musculus
Acetylcholinesterase

PDB Structure

PDB 2GYV
External Links
Method X-RAY DIFFRACTION
Organism Homo
Primary Citation
Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates.
Ekstrom, F., Pang, Y.P., Boman, M., Artursson, E., Akfur, C., Borjegren, S.
Biochem.Pharm.