CATH Domain 2gvqC01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.970	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3
	1.20.970.10	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C

Domain Context

CATH Clusters

Superfamily	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family

Enzyme Information

2.4.2.18

Anthranilate phosphoribosyltransferase.

based on mapping to UniProt P50384

N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.

-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

P50384

TRPD_SACS2

Saccharolobus solfataricus P2

Anthranilate phosphoribosyltransferase

PDB Structure

PDB	2GVQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. Marino, M., Deuss, M., Svergun, D.I., Konarev, P.V., Sterner, R., Mayans, O. J.Biol.Chem.