CATH Domain 2gt8A01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Replicase polyprotein 1a

Enzyme Information

UniProtKB Entries (1)

Q6T1E9_CVHSA

SARS coronavirus CUHK-L2

Orf1ab polyprotein

PDB Structure

PDB	2GT8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase. Lee, T.W., Cherney, M.M., Liu, J., James, K.E., Powers, J.C., Eltis, L.D., James, M.N.G. J.Mol.Biol.