CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Glutathione S-transferase P

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P80031
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P80031
GSTP1_PIG
Sus scrofa
Glutathione S-transferase P

PDB Structure

PDB 2GSR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution.
Dirr, H., Reinemer, P., Huber, R.
J.Mol.Biol.