1 keywords

CATH Domain 2gk9C01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.800 Phosphatidylinositol Phosphate Kinase II Beta
Homologous Superfamily 3.30.800.10 Phosphatidylinositol Phosphate Kinase II Beta

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol Phosphate Kinase II Beta
Functional Family Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Enzyme Information

2.7.1.149
1-phosphatidylinositol-5-phosphate 4-kinase.
based on mapping to UniProt Q8TBX8
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.

UniProtKB Entries (1)

Q8TBX8
PI42C_HUMAN
Homo sapiens
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

PDB Structure

PDB 2GK9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
Thorsell, A.G., Uppenberg, J., Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Persson, C., Hallberg, B.M.
To be Published