1 keywords

CATH Domain 2gk9A02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.810 Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2
Homologous Superfamily 3.30.810.10 2-Layer Sandwich

Domain Context

CATH Clusters

Superfamily 2-Layer Sandwich
Functional Family

Enzyme Information

2.7.1.149
1-phosphatidylinositol-5-phosphate 4-kinase.
based on mapping to UniProt Q8TBX8
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.

UniProtKB Entries (1)

Q8TBX8
PI42C_HUMAN
Homo sapiens
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

PDB Structure

PDB 2GK9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
Thorsell, A.G., Uppenberg, J., Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Persson, C., Hallberg, B.M.
To be Published