CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Phosphatidyl-myo-inositol mannosyltransferase

Enzyme Information

2.4.1.345
Phosphatidyl-myo-inositol alpha-mannosyltransferase.
based on mapping to UniProt A0QWG6
GDP-alpha-D-mannose + 1-phosphatidyl-1D-myo-inositol = GDP + 2-O-(alpha- D-mannosyl)-1-phosphatidyl-1D-myo-inositol.
-!- The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). -!- Formerly EC 2.4.1.57.

UniProtKB Entries (1)

A0QWG6
PIMA_MYCS2
Mycolicibacterium smegmatis MC2 155
Phosphatidyl-myo-inositol mannosyltransferase

PDB Structure

PDB 2GEK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
Guerin, M.E., Kordulakova, J., Schaeffer, F., Svetlikova, Z., Buschiazzo, A., Giganti, D., Gicquel, B., Mikusova, K., Jackson, M., Alzari, P.M.
J.Biol.Chem.