CATH Classification

Domain Context

CATH Clusters

Superfamily Formyl transferase, N-terminal domain
Functional Family Phosphoribosylglycinamide formyltransferase

Enzyme Information

2.1.2.2
Phosphoribosylglycinamide formyltransferase.
based on mapping to UniProt P08179
10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.

UniProtKB Entries (1)

P08179
PUR3_ECOLI
Escherichia coli K-12
Phosphoribosylglycinamide formyltransferase

PDB Structure

PDB 2GAR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.
Su, Y., Yamashita, M.M., Greasley, S.E., Mullen, C.A., Shim, J.H., Jennings, P.A., Benkovic, S.J., Wilson, I.A.
J.Mol.Biol.