1 keywords

CATH Domain 2g59A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.190 Protein-Tyrosine Phosphatase; Chain A
Homologous Superfamily 3.90.190.10 Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family receptor-type tyrosine-protein phosphatase O isoform X1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q16827
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q16827
PTPRO_HUMAN
Homo sapiens
Receptor-type tyrosine-protein phosphatase O

PDB Structure

PDB 2G59
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural genomics of protein phosphatases.
Almo, S.C., Bonanno, J.B., Sauder, J.M., Emtage, S., Dilorenzo, T.P., Malashkevich, V., Wasserman, S.R., Swaminathan, S., Eswaramoorthy, S., Agarwal, R., Kumaran, D., Madegowda, M., Ragumani, S., Patskovsky, Y., Alvarado, J., Ramagopal, U.A., Faber-Barata, J., Chance, M.R., Sali, A., Fiser, A., Zhang, Z.Y., Lawrence, D.S., Burley, S.K.
J.Struct.Funct.Genom.