CATH Classification

Domain Context

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family

Enzyme Information

3.2.1.20
Alpha-glucosidase.
based on mapping to UniProt P0CD66
Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
-!- Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all. -!- The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links.

UniProtKB Entries (1)

P0CD66
AGLU_SACS2
Saccharolobus solfataricus P2
Alpha-glucosidase

PDB Structure

PDB 2G3N
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
Ernst, H.A., Lo Leggio, L., Willemoes, M., Leonard, G., Blum, P., Larsen, S.
J.Mol.Biol.