CATH Classification

Domain Context

CATH Clusters

Superfamily Chloramphenicol acetyltransferase-like domain
Functional Family Carnitine O-acetyltransferase

Enzyme Information

2.3.1.6
Choline O-acetyltransferase.
based on mapping to UniProt P28329
Acetyl-CoA + choline = CoA + O-acetylcholine.
-!- Propanoyl-CoA can act, more slowly, in place of acetyl-CoA.

UniProtKB Entries (1)

P28329
CLAT_HUMAN
Homo sapiens
Choline O-acetyltransferase

PDB Structure

PDB 2FY4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Substrate binding and catalytic mechanism of human choline acetyltransferase.
Kim, A.R., Rylett, R.J., Shilton, B.H.
Biochemistry