CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome-c3 Hydrogenase, chain B
Functional Family Hydrogenase 2 large subunit

Enzyme Information

1.12.2.1
Cytochrome-c3 hydrogenase.
based on mapping to UniProt P12944
H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P12944
PHNL_DESGI
Desulfovibrio gigas
Periplasmic [NiFe] hydrogenase large subunit

PDB Structure

PDB 2FRV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the [Nife] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe Ligands
Volbeda, A., Garcin, E., Piras, C., De Lacey, A.L., Fernandez, V.M., Hatchikian, E.C., Frey, M., Fontecilla-Camps, J.C.
J.Am.Chem.Soc.