CATH Domain 2frvA02

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.480	Cytochrome-c3 Hydrogenase; Chain A, domain 2
	4.10.480.10	Cytochrome-c3 hydrogenase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 hydrogenase, C-terminal domain
Functional Family

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P12943

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P12944

PHNL_DESGI

Desulfovibrio gigas

Periplasmic [NiFe] hydrogenase large subunit

PDB Structure

PDB	2FRV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of the [Nife] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe Ligands Volbeda, A., Garcin, E., Piras, C., De Lacey, A.L., Fernandez, V.M., Hatchikian, E.C., Frey, M., Fontecilla-Camps, J.C. J.Am.Chem.Soc.