CATH Domain 2fpgA02

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.261	Succinyl-CoA synthetase domains

Domain Context

CATH Clusters

Superfamily	Succinyl-CoA synthetase domains
Functional Family	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

Enzyme Information

6.2.1.4	Succinate--CoA ligase (GDP-forming). based on mapping to UniProt O19069 GTP + succinate + CoA = GDP + phosphate + succinyl-CoA. -!- Itaconate can act instead of succinate and ITP instead of GTP.
6.2.1.5	Succinate--CoA ligase (ADP-forming). based on mapping to UniProt O19069 ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

UniProtKB Entries (1)

SUCA_PIG

Sus scrofa

Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

PDB Structure

PDB	2FPG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Interactions of GTP with the ATP-grasp Domain of GTP-specific Succinyl-CoA Synthetase Fraser, M.E., Hayakawa, K., Hume, M.S., Ryan, D.G., Brownie, E.R. J.Biol.Chem.