CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family

Enzyme Information

3.1.22.4
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt Q5KXY4
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.

UniProtKB Entries (1)

Q5KXY4
RECU_GEOKA
Geobacillus kaustophilus HTA426
Holliday junction resolvase RecU

PDB Structure

PDB 2FCO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure, flexibility, and mechanism of the Bacillus stearothermophilus RecU Holliday junction resolvase.
Kelly, S.J., Li, J., Setlow, P., Jedrzejas, M.J.
Proteins