CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarate reductase/succinate dehydrogenase, transmembrane subunit
Functional Family Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

Enzyme Information

UniProtKB Entries (1)

Q9YHT2
SDHB_CHICK
Gallus gallus
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

PDB Structure

PDB 2FBW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme.
Huang, L.S., Sun, G., Cobessi, D., Wang, A.C., Shen, J.T., Tung, E.Y., Anderson, V.E., Berry, E.A.
J.Biol.Chem.