CATH Classification

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Putative glucosylceramidase 3

Enzyme Information

3.2.1.45
Glucosylceramidase.
based on mapping to UniProt P04062
D-glucosyl-N-acylsphingosine + H(2)O = D-glucose + N-acylsphingosine.
-!- Also acts on glucosylsphingosine (cf. EC 3.2.1.62).

UniProtKB Entries (1)

P04062
GLCM_HUMAN
Homo sapiens
Glucosylceramidase

PDB Structure

PDB 2F61
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
Analyses of Variant Acid beta-Glucosidases: EFFECTS OF GAUCHER DISEASE MUTATIONS.
Liou, B., Kazimierczuk, A., Zhang, M., Scott, C.R., Hegde, R.S., Grabowski, G.A.
J.Biol.Chem.