CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.600.40
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt O52512
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

O52512
T2S1_STRFI
Streptomyces fimbriatus
Type-2 restriction enzyme SfiI

PDB Structure

PDB 2F03
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA.
Vanamee, E.S., Viadiu, H., Kucera, R., Dorner, L., Picone, S., Schildkraut, I., Aggarwal, A.K.
Embo J.