CATH Classification

Domain Context

CATH Clusters

Superfamily PtsI, HPr-binding domain
Functional Family Phosphoenolpyruvate-protein phosphotransferase

Enzyme Information

2.7.3.9
Phosphoenolpyruvate--protein phosphotransferase.
based on mapping to UniProt P08839
Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)- phospho-L-histidine.
-!- Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport. -!- A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme.

UniProtKB Entries (1)

P08839
PT1_ECOLI
Escherichia coli K-12
Phosphoenolpyruvate-protein phosphotransferase

PDB Structure

PDB 2EZB
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
Tjandra, N., Garrett, D.S., Gronenborn, A.M., Bax, A., Clore, G.M.
Nat.Struct.Biol.