CATH Classification

Domain Context

CATH Clusters

Superfamily Anthranilate synthase
Functional Family Isochorismate synthase MenF

Enzyme Information

5.4.4.2
Isochorismate synthase.
based on mapping to UniProt P38051
Chorismate = isochorismate.
-!- The reaction is reversible. -!- Formerly EC 5.4.99.6.

UniProtKB Entries (1)

P38051
MENF_ECOLI
Escherichia coli K-12
Isochorismate synthase MenF

PDB Structure

PDB 2EUA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.
Kolappan, S., Zwahlen, J., Zhou, R., Truglio, J.J., Tonge, P.J., Kisker, C.
Biochemistry