CATH Classification

Domain Context

CATH Clusters

Superfamily DHBP synthase
Functional Family Threonylcarbamoyl-AMP synthase

Enzyme Information

2.7.7.87
L-threonylcarbamoyladenylate synthase.
based on mapping to UniProt Q970S6
L-threonine + ATP + HCO(3)(-) = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
-!- The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg).

UniProtKB Entries (1)

Q970S6
SUA5_SULTO
Sulfurisphaera tokodaii str. 7
Threonylcarbamoyl-AMP synthase

PDB Structure

PDB 2EQA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7
Agari, Y., Sato, S., Wakamatsu, T., Bessho, Y., Ebihara, A., Yokoyama, S., Kuramitsu, S., Shinkai, A.
Proteins