CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.770 |
Domain Context
CATH Clusters
| Superfamily | 1.10.8.770 |
| Functional Family | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like |
Enzyme Information
| 6.3.4.3 |
Formate--tetrahydrofolate ligase.
based on mapping to UniProt Q3V3R1
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
-!- In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity.
|
UniProtKB Entries (1)
| Q3V3R1 |
C1TM_MOUSE
Mus musculus
Monofunctional C1-tetrahydrofolate synthase, mitochondrial
|
PDB Structure
| PDB | 2EO2 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure of the insertion region (510-573) of FTHFS domain from mouse methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein
To be Published
|