CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Tyrosine-protein kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P51813
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P51813
BMX_HUMAN
Homo sapiens
Cytoplasmic tyrosine-protein kinase BMX

PDB Structure

PDB 2EKX
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the human BMX SH2 domain
Kasai, T., Koshiba, S., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S.
To be Published