CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q5KWX7
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q5KWX7
AROE_GEOKA
Geobacillus kaustophilus HTA426
Shikimate dehydrogenase (NADP(+))

PDB Structure

PDB 2EGG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Geobacillus kaustophilus
Bagautdinov, B., Kunishima, N.
To be Published