CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.8.1.5
Haloalkane dehalogenase.
based on mapping to UniProt P22643
1-haloalkane + H(2)O = a primary alcohol + halide.
-!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds.

UniProtKB Entries (1)

P22643
DHLA_XANAU
Xanthobacter autotrophicus
Haloalkane dehalogenase

PDB Structure

PDB 2EDC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site.
Verschueren, K.H., Kingma, J., Rozeboom, H.J., Kalk, K.H., Janssen, D.B., Dijkstra, B.W.
Biochemistry