CATH Classification

Domain Context

CATH Clusters

Superfamily Electron Transport, Fmn-binding Protein; Chain A
Functional Family

Enzyme Information

1.5.1.36
Flavin reductase (NADH).
based on mapping to UniProt Q5SJP7
Reduced flavin + NAD(+) = flavin + NADH.
-!- The enzyme from Escherichia coli W catalyzes the reduction of free flavins by NADH. -!- The enzyme has similar affinity to FAD, FMN and riboflavin. -!- Activity with NADPH is more than 2 orders of magnitude lower than activity with NADH.

UniProtKB Entries (1)

Q5SJP7
HPAC_THET8
Thermus thermophilus HB8
4-hydroxyphenylacetate 3-monooxygenase, reductase component

PDB Structure

PDB 2ED4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity
Kim, S.H., Hisano, T., Iwasaki, W., Ebihara, A., Miki, K.
Proteins