CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarylacetoacetase-like, C-terminal domain
Functional Family 2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Enzyme Information

4.2.1.163
2-oxo-hept-4-ene-1,7-dioate hydratase.
based on mapping to UniProt Q46982
(4Z)-2-oxohept-4-enedioate + H(2)O = (4S)-4-hydroxy-2-oxoheptanedioate.
-!- Part of a 4-hydroxyphenylacetate degradation pathway in Escherichia coli C.

UniProtKB Entries (1)

Q46982
Q46982_ECOLX
Escherichia coli
2-hydroxyhexa-2,4-dienoate hydratase

PDB Structure

PDB 2EB4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli
Izumi, A., Rea, D., Adachi, T., Unzai, S., Park, S.Y., Roper, D.I., Tame, J.R.H.
J.Mol.Biol.