CATH Domain 2e8aA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.40	ATPase, nucleotide binding domain

Domain Context

CATH Clusters

Superfamily	3.30.420.40
Functional Family	Heat shock 70 kDa protein 1A

Enzyme Information

UniProtKB Entries (1)

HS71B_HUMAN

Homo sapiens

Heat shock 70 kDa protein 1B

PDB Structure

PDB	2E8A
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Shida, M., Arakawa, A., Ishii, R., Kishishita, S., Takagi, T., Kukimoto-Niino, M., Sugano, S., Tanaka, A., Shirouzu, M., Yokoyama, S. Acta Crystallogr.,Sect.D