CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.2280
Functional Family ATP-dependent RNA helicase DDX50

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q9BQ39
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9BQ39
DDX50_HUMAN
Homo sapiens
ATP-dependent RNA helicase DDX50

PDB Structure

PDB 2E29
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the GUCT domain from human RNA helicase II/Gubeta reveals the RRM fold, but implausible RNA interactions
Ohnishi, S., Paakkonen, K., Koshiba, S., Tochio, N., Sato, M., Kobayashi, N., Harada, T., Watanabe, S., Muto, Y., Guntert, P., Tanaka, A., Kigawa, T., Yokoyama, S.
Proteins