CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P59071
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P59071
PA2B8_DABRR
Daboia russelii
Basic phospholipase A2 VRV-PL-VIIIa

PDB Structure

PDB 2DPZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Phospholipase A2 as a target protein for non-steroidal anti-inflammatory drugs (NSAIDs): Crystal structure of the complex formed between a group II phospholipase A2 and N-(4-hydroxyphenyl) - acetamide at 2.1 resolution
Singh, N., Sharma, S., Singh, T.P.
To be Published