CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.2.98.1
Formaldehyde dismutase.
based on mapping to UniProt Q52078
2 formaldehyde + H(2)O = formate + methanol.
-!- Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP(+) by reaction with a second formaldehyde, yielding methanol. -!- The enzyme from Mycobacterium sp. DSM 3803 also catalyzes the reactions of EC 1.1.99.36 and EC 1.1.99.37. -!- Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors. -!- Formerly EC 1.2.99.4.

UniProtKB Entries (1)

Q52078
FDM_PSEPU
Pseudomonas putida
Formaldehyde dismutase

PDB Structure

PDB 2DPH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The X-ray crystal structure of formaldehyde dismutase at 2.3 A resolution
Hasegawa, T., Yamano, A., Miura, K., Katsube, Y., Yanase, H., Kato, N.
Acta Crystallogr.,Sect.A