CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tyrosine--tRNA ligase

Enzyme Information

6.1.1.1
Tyrosine--tRNA ligase.
based on mapping to UniProt P36421
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

P36421
SYYC_YEAST
Saccharomyces cerevisiae S288C
Tyrosine--tRNA ligase, cytoplasmic

PDB Structure

PDB 2DLC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms.
Tsunoda, M., Kusakabe, Y., Tanaka, N., Ohno, S., Nakamura, M., Senda, T., Moriguchi, T., Asai, N., Sekine, M., Yokogawa, T., Nishikawa, K., Nakamura, K.T.
Nucleic Acids Res.