CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q80W21
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q80W21
GSTM7_MOUSE
Mus musculus
Glutathione S-transferase Mu 7

PDB Structure

PDB 2DC5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
Kamo, S., Kishishita, S., Murayama, K., Shirouzu, M., Yokoyama, S.
To be Published