CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.47.10
Functional Family Chalcone synthase 1

Enzyme Information

2.3.1.216
5,7-dihydroxy-2-methylchromone synthase.
based on mapping to UniProt Q58VP7
5 malonyl-CoA = 5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO(2) + H(2)O.
-!- A polyketide synthase from the plant Aloe arborescens (aloe).

UniProtKB Entries (1)

Q58VP7
PCS_ALOAR
Aloe arborescens
5,7-dihydroxy-2-methylchromone synthase

PDB Structure

PDB 2D3M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens
Morita, H., Kondo, S., Oguro, S., Noguchi, H., Sugio, S., Abe, I., Kohno, T.
Chem.Biol.