CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Cutinase 1

Enzyme Information

3.1.1.74
Cutinase.
based on mapping to UniProt P00590
Cutin + H(2)O = cutin monomers.
-!- Cutin, a polymeric structural component of plant cuticles, is an hydroxy fatty acid polymer, usually C(16) or C(18) and that contains one to three hydroxyl groups. -!- The enzyme from several fungal sources also hydrolyzes the p-nitrophenyl esters of hexadecanoic acid. -!- It is however inactive toward several esters that are substrates for non-specific esterases.

UniProtKB Entries (1)

P00590
CUTI1_FUSSO
[Nectria] haematococca mpVI
Cutinase 1

PDB Structure

PDB 2CUT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cutinase, a lipolytic enzyme with a preformed oxyanion hole.
Martinez, C., Nicolas, A., van Tilbeurgh, H., Egloff, M.P., Cudrey, C., Verger, R., Cambillau, C.
Biochemistry