CATH Classification

Domain Context

CATH Clusters

Superfamily BRCT domain
Functional Family DNA nucleotidylexotransferase

Enzyme Information

2.7.7.31
DNA nucleotidylexotransferase.
based on mapping to UniProt P04053
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Nucleoside may be ribo- or deoxyribo-.

UniProtKB Entries (1)

P04053
TDT_HUMAN
Homo sapiens
DNA nucleotidylexotransferase

PDB Structure

PDB 2COE
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of BRCT domain of terminal deoxynucleotidyltransferase
Nagashima, T., Hayashi, F., Yokoyama, S.
To be Published