CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

Enzyme Information

3.5.3.18
Dimethylargininase.
based on mapping to UniProt P56965
N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.
-!- Also acts on N(omega)-methyl-L-arginine.

UniProtKB Entries (1)

P56965
DDAH1_BOVIN
Bos taurus
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

PDB Structure

PDB 2CI1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
Frey, D., Braun, O., Briand, C., Vasak, M., Grutter, M.G.
Structure